Glossary
Prosomeres
Segments of the developing forebrain that has been subdivided into specific territories.
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Receptor Smads or receptor regulate smads
In response to signals by the TGF-β superfamily of ligands these proteins associate with receptor kinases and are phosphorylated to alter downstream gene transcription.
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Retinoic acid (RA)
A vitamin A derivative, that is a regulator substance in morphogenesis and functions in the growth and development of bone and the maintenance of epithelium as well as neural specification and differentiation.
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Rho kinases
Serine / threoine kinases which are cativated by binding to the GTP bound form of RhoA.
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Rhombencephalon
The portion of the embryonic brain from which the metencephalon and myelencephalon develop, including the pons, cerebellum, and the medulla oblongata. Also called the hindbrain.
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Rhombomeres
In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube (a neuromere) in the area that will eventually become the rhombencephalon.
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Roof plate
A signalling centre induced in the most dorsal region of the neural tube by BMP signals from the overlying ectoderm.
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Secreted frizzled-related protein 2 (SFRP2)
A Wnt signalling antagonist that binds to Wnt signalling molecules.
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Shroom familly
A family of actin binding proteins
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Single nucleotide polymorphisms (SNPs)
A single base-pair difference between two copies of a deoxyribonucleic acid sequence from two individuals.